Abstract 11711: Quantification of Atherosclerotic Coronary Artery Disease in the Pre/Peri-Menopausal Female Using Cardiac CTA

• DOI: 10.1161/circ.144.suppl_1.11711
• Publication Date: 2022-03-19T23:58:21Z
• Authors: Anup Solsi; Roger Bies; Ralph Drosten; Rachel M Bond; Femi Oladokun; Robert Roberts; Pallavi Bellamkonda
• Keywords: Phoenix; Interventional cardiology

Introduction: Coronary Artery Disease (CAD) occurs equally in males and females is the most common cause of death both genders worldwide. The pre/peri-menopausal female believed to have minimal coronary atherosclerosis based primarily on non-invasive techniques, with limited angiography data. Cardiac computed tomography (CCTA) a more sensitive, anatomical diagnostic tool for quantifying atherosclerosis, but women been underrepresented underdiagnosed. goal this study was quantify population. Methods: We conducted retrospective chart review 510 aged 35-60 presenting atypical chest pain shortness breath. These were consecutive admissions which CCTA performed from January 2014 December 2019. degree quantified using CAD-RADS scoring system. Results: Analysis showed 68.82% patients had no evidence atherosclerosis. 4.31% CAD, 18.24% mild 6.47% moderate CAD 2.16% found severe CAD. Each category stenosis typically multiple vessels involved. Over 65% Non-Hispanic White, 27% Hispanic, 8% African American 4% Asian. Less than 5% discharged statin therapy. Conclusions: This first female. Quantification angiograms obtained by CCTA, currently sensitive imaging technique. Despite perceived protective nature premenopausal state women, 30% detectable CCTA. 10% greater 50% (moderate CAD), suggesting potential future ischemic heart disease. So few therapy, showing paucity guideline therapy used results suggest targeting preventative even late pre or peri-menopausal stage, such as favorable lifestyle changes reducing known modifiable cardiac risk factors, should significantly prevent progression its subsequent sequelae menopause.