Sepsis-Related Myocardial Calcification

• DOI: 10.1161/circheartfailure.111.962183
• Publication Date: 2011-09-20T20:51:22Z
• Authors: Rob C.M. van Krui...; Joris J. van der ...; Ruben Uijlings; Luuk C. Otterspoor
• Keywords: Male; Calcinosis; Middle Aged; Shigella flexneri; 3. Good health; Electrocardiography; 03 medical and health sciences; 0302 clinical medicine; Echocardiography; Sepsis; Humans; Calcium; Cardiomyopathies; Tomography, X-Ray Computed; Dysentery, Bacillary

A 56-year-old man was admitted on our intensive care unit with septic shock after 10 days of diarrhea, shortly after he had visited India. He had no relevant previous medical history. Blood and fecal cultures grew various pathogens, including Shigella flexneri. ECG showed diffuse ST elevation with PR depression (Figure 1), and laboratory results revealed significant troponin (peak level of 5.72 ng/mL) and creatine phosphokinase-MB (peak level of 117 ng/mL) release, most likely caused by a perimyocarditis in the setting of Shigella sepsis. Further diagnostic evaluation revealed hairy cell leukemia. …