Discrepant Measurements of Maximal Left Ventricular Wall Thickness Between Cardiac Magnetic Resonance Imaging and Echocardiography in Patients With Hypertrophic Cardiomyopathy

• DOI: 10.1161/circimaging.117.006309
• Publication Date: 2017-08-10T01:20:09Z
• Authors: Waseem Hindieh; Adaya Weissler-Snir; Helene Hammer; Arnon Adler; Harry Rakowski; Raymond H. Chan
• Keywords: Cardiac magnetic resonance

We sought to compare maximal left ventricular (LV) wall thickness (WT) measurements as obtained by routine clinical practice between echocardiography and cardiac magnetic resonance (CMR) document causes of discrepancy.One-hundred ninety-five patients with hypertrophic cardiomyopathy (median age, 52.8±15.1 years) who underwent CMR imaging within 6 months (median, 41 days; interquartile range, 16-97 days) were included. LVWT was assessed in parasternal long short axis 2-dimensional CMR. By Bland-Altman plot, mean difference 0.5 mm (95% confidence interval, -6.9, 7.8) equal distribution discrepancy along the full range LVWT. Ninety-seven (49.7%) identified have intermodal measurement discrepancies ≥10%. In 7 (7.2%), reported inaccurate because interpretation error. 90 (92.8%), underestimated (n=32; 33.0%) or overestimated (n=58; 59.8%) Underestimation focal LV hypertrophy (n=10; 10.3%) poor acoustic windows (n=22; 22.7%) while overestimation resulted from inclusion right myocardium (n=37; 38.1%), trabeculations (n=5; 5.2%), papillary muscle (n=3; 3.1%), apical-septal bundle (n=1; 1.0%), well plane obliquity (n=7; 12.5%). 31 (15.9%) patients, occurred at diagnostic prognostic cut-offs.Although general measured similar CMR, discordance limitations technique present a significant subset patients. As impacts diagnosis sudden death management, should be considered part evaluation all cardiomyopathy.