Percutaneous Pulmonary Valve Implantation

• DOI: 10.1161/circulationaha.107.735779
• Publication Date: 2008-04-08T00:53:31Z
• Authors: Philipp Lurz; Louise Coats; Sachin Khambadkone; Johannes Nordmeyer; Younes Boudjemline; Silvia Schievano; Vivek Muthurangu; Twin Yen Lee; Giovanni Parenzan; Graham Derrick; Seamus Cullen; Fiona Walker; Victor Tsang; John Deanfield; Andrew M. Taylor; Philipp Bonhoeffer
• Keywords: Ventricular outflow tract; Pulmonary valve

Background— Percutaneous pulmonary valve implantation was introduced in the year 2000 as a nonsurgical treatment for patients with right ventricular outflow tract dysfunction. Methods and Results— Between September February 2007, 155 stenosis and/or regurgitation underwent percutaneous implantation. This led to significant reduction systolic pressure (from 63±18 45±13 mm Hg, P <0.001) gradient 37±20 17±10 <0.001). Follow-up ranged from 0 83.7 months (median 28.4 months). Freedom reoperation 93% (±2%), 86% (±3%), 84% (±4%), 70% (±13%) at 10, 30, 50, 70 months, respectively. transcatheter reintervention 95% 87% 73% (±6%), (±6%) Survival 83 96.9%. On time-dependent analysis, first series of 50 (log-rank test residual >25 Hg =0.01) were associated higher risk reoperations. Conclusions— resulted ability avoid surgical revision majority cases. procedure might reduce number operations needed over total lifetime ventricle–to–pulmonary artery conduits.