Long-Term Outcomes of Coronary-Artery Bypass Graft Surgery Versus Percutaneous Coronary Intervention for Multivessel Coronary Artery Disease in the Bare-Metal Stent Era

Adult Aged, 80 and over Male Adolescent Age Factors Coronary Artery Disease Middle Aged Survival Analysis 3. Good health 03 medical and health sciences Treatment Outcome 0302 clinical medicine Metals Humans Female Stents Longitudinal Studies Registries Angioplasty, Balloon, Coronary Coronary Artery Bypass Child Aged
DOI: 10.1161/circulationaha.107.735902 Publication Date: 2008-09-30T01:11:46Z
ABSTRACT
Background— Observational registries comparing coronary artery bypass graft (CABG) surgery and percutaneous intervention (PCI) have reported long-term survival results that are discordant with those of randomized trials. Methods Results— We conducted a multicenter study in Japan enrolling consecutive patients undergoing first CABG or PCI between January 2000 December 2002. Among 9877 enrolled, 5420 (PCI: 3712, CABG: 1708) had multivessel disease without left main involvement. Because age is an important determinant when choosing revascularization strategies, analysis was stratified by either ≥75 <75 years. Analyses were also performed other relevant subgroups. Median follow-up interval 1284 days 95% rate at 2 At 3 years, unadjusted rates 91.7% 89.6% the groups, respectively (log rank P =0.26). After adjustment for baseline characteristics, outcome tended to be better after (hazard ratio death versus [HR], confidence [CI]: 1.23 [0.99-1.53], =0.06). Adjusted outcomes among elderly (HR [95%CI]: 1.37 [0.98-1.92] =0.07), but not nonelderly [95% CI]: 1.09 [0.82-1.46], =0.55). Unadjusted adjusted significantly different any subgroups excluded from analysis. Conclusions— In CREDO-Kyoto registry, years similar CABG, result consistent
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