Transcatheter Aortic Valve Implantation

• DOI: 10.1161/circulationaha.108.837807
• Publication Date: 2009-06-02T01:42:13Z
• Authors: John G. Webb; Lukas Altwegg; Robert H. Boone; Anson Cheung; Jian Ye; Samuel Lichtenstein; May Lee; Jean Bernard Masson; Christopher Thompson; Robert Moss; Ron Carere; Brad Munt; Fabian Nietlispach; Karin Humphries
• Keywords: Aged, 80 and over; Heart Valve Prosthesis Implantation; Male; Cardiac Catheterization; Aortic Valve Stenosis; Comorbidity; Kaplan-Meier Estimate; 3. Good health; 03 medical and health sciences; Postoperative Complications; 0302 clinical medicine; Echocardiography; Risk Factors; Aortic Valve; Cause of Death; Humans; Female; Registries; Aged

Transcatheter aortic valve implantation is an alternative to open heart surgery in patients with stenosis. However, long-term data on a programmatic approach remain sparse.Transcatheter was performed 168 (median age, 84 years) the setting of severe stenosis and high surgical risk. Access transarterial (n=113) or, presence small iliofemoral artery diameter, transapical (n=55). The overall success rate 94.1% this early experience. Intraprocedural mortality 1.2%. Operative (30-day) 11.3%, lower group than (8.0% versus 18.2%; P=0.07). Overall fell from 14.3% initial half 8.3% second experience, 12.3% 3.6% (P=0.16) 25% 11.1% (P=0.30) patients. Functional class improved over 1-year postprocedure period (P<0.001). Survival at 1 year 74%. bulk late readmission not procedure or related but rather due comorbidities. Paravalvular regurgitation common generally mild remained stable follow-up. At maximum >3 years median 221 days, structural failure observed.Transcatheter can result sustained functional improvement high-risk Late outcome determined primarily by comorbidities unrelated disease.