Adverse Childhood Experiences and Blood Pressure Trajectories From Childhood to Young Adulthood

• DOI: 10.1161/circulationaha.114.013104
• Publication Date: 2015-04-10T02:11:59Z
• Authors: Shaoyong Su; Xiaoling Wang; Jennifer S. Pollock; Frank A. Treiber; Xiaojing Xu; Harold Snieder; W. Vaughn McCall; Michael Stefanek; Gregory A. Harshf...
• Keywords: Longitudinal Study

The purposes of this study were to assess the long-term effect adverse childhood experiences (ACEs) on blood pressure (BP) trajectories from young adulthood and examine whether relation is explained by socioeconomic status (SES) or risk behaviors that are associated with ACEs.Systolic diastolic BPs measured up 16 times (13 average) over a 23-year period in 213 African Americans 181 European 5 38 years age. Retrospective data traumatic before 18 age collected, including abuse, neglect, household dysfunction. Individual growth curve modeling within multilevel framework was used between exposure ACEs BP development. No main average levels found. However, significant interaction ACE score age(3) observed (systolic BP, P=0.033; P=0.017). Subjects who experienced multiple events during showed faster rise after 30 than those without ACEs. As expected, graded association negative health (P<0.001). ACE-systolic not these factors, whereas ACE-diastolic partially mediated illicit drug use.In novel longitudinal study, we participants exposed displayed greater increase compared their counterparts