Prevalence of Hypertensive Phenotypes After Preeclampsia

• DOI: 10.1161/hypertensionaha.117.09799
• Publication Date: 2017-11-13T10:05:20Z
• Authors: Agnès Ditisheim; Grégoire Wuerzner; Belen Ponte; Yvan Vial; Olivier Irion; Michel Burnier; Michel Boulvain; Antoinette Pechèr...
• Keywords: Adult; Pre-Eclampsia/epidemiology; Blood Pressure; Postpartum Period/physiology; Cohort Studies; 03 medical and health sciences; Switzerland/epidemiology; 0302 clinical medicine; Pre-Eclampsia; Pregnancy; Risk Factors; info:eu-repo/classification/ddc/616; info:eu-repo/classification/ddc/618; Prevalence; risk factors; Humans; info:eu-repo/classification/ddc/613; Prospective Studies; Blood Pressure Monitoring, Ambulatory/methods; Hypertension/classification; Blood Pressure/physiology; Antihypertensive Agents; ddc:613; ddc:616; Antihypertensive Agents/therapeutic use; ddc:618; Postpartum Period; Blood Pressure Monitoring, Ambulatory; 3. Good health; Phenotype; Hypertension; Cohort studies; Female; pregnancy; Switzerland

Preeclampsia is associated with increased cardiovascular and renal risk. The aim of this prospective cohort study was to characterize the early postpartum blood pressure (BP) profile after preeclampsia. We enrolled 115 women preeclampsia 41 a normal pregnancy in study. At 6 12 week postpartum, we assessed prevalence different hypertensive phenotypes using 24-hour ambulatory BP monitoring (ABPM), as well risk salt sensitivity variability derived from ABPM parameters. Among patients preeclampsia, 57.4% were still at office. Daytime ABP significantly higher group (118.9±15.0/83.2±10.4 mm Hg) than controls (104.8±7.9/71.6±5.3 Hg; P <0.01). Differences between groups similar for nocturnal values. Fifty percent remained on whom 24.3% under antihypertensive treatment; 17.9% displayed white-coat hypertension 11.6% had masked hypertension. In controls, 2.8% hypertension; none or needed treatment. nondippers 59.8% versus 51.4% controls. High-risk class (48.6%) compared (17.1%); <0.01. conclusion, weeks delivery reveals high rate sustained ambulatory, nocturnal, This finding may help identify who should be included management program. Clinical Trial Registration— URL: https://www.clinicaltrials.gov . Unique identifier: NCT01095939.