Role of ST‐Segment Resolution Alone and in Combination With TIMI Flow After Primary Percutaneous Coronary Intervention for ST‐Segment–Elevation Myocardial Infarction

• DOI: 10.1161/jaha.123.029670
• Publication Date: 2023-07-14T11:00:47Z
• Authors: Chao Wu; Xiaojin Gao; Ling Li; Quanmin Jing; Weimin Li; Haiyan Xu; Wenbo Zhang; Sidong Li; Yanyan Zhao; Yang Wang; Wei Li; Yongjian Wu; Fenghuan Hu; Chen Jin; Shubin Qiao; Jingang Yang; Yuejin Yang
• Keywords: TIMI

Background To evaluate the role of ST-segment resolution (STR) alone and in combination with Thrombolysis Myocardial Infarction (TIMI) flow reperfusion evaluation after primary percutaneous coronary intervention (PPCI) for ST-segment-elevation myocardial infarction by investigating long-term prognostic impact. Methods Results From January 2013 through September 2014, we studied 5966 patients enrolled CAMI (China Acute Infarction) registry available data STR evaluated at 120 minutes PPCI. Successful included ≥50% complete (ST-segment back to equipotential line). After PPCI, TIMI was assessed. The outcome 2-year all-cause mortality. < 50%, ≥50%, occurred 20.6%, 64.3%, 15.1% patients, respectively. By multivariable analysis, (5.6%; adjusted hazard ratio [HR], 0.45 [95% CI, 0.36-0.56]) (5.1%; HR, 0.48 0.34-0.67]) were significantly associated lower mortality than <50% (11.7%). an independent predictor across spectrum clinical variables. combining STR, different observed subgroups, lowest successful 3 flow, intermediate when either these measures reduced, highest both abnormal. Conclusions Post-PPCI is a robust prognosticator infarction, whereas integrated analysis plus yields incremental information beyond measure alone, supporting it as convenient reliable surrogate end point defining Registration URL: https://www.clinicaltrials.gov; Unique identifier: NCT01874691.