Women With Large Vessel Occlusion Acute Ischemic Stroke Are Less Likely to Be Routed to Comprehensive Stroke Centers

• DOI: 10.1161/jaha.123.029830
• Publication Date: 2023-07-18T09:30:11Z
• Authors: Muhammad Bilal Tariq; Iman Ali; Sergio Salazar‐Ma...; Ananya S. Iyyangar; Hussain M. Azeem; Swapnil Khose; Victor Lopez; Rania Abdelkhaleq; Louise D. McCullough; Sunil A. Sheth; Youngran Kim
• Keywords: Stroke

Background Prehospital routing of patients with large vessel occlusion (LVO) acute ischemic stroke (AIS) to centers capable performing endovascular therapy may improve clinical outcomes. Here, we explore whether distance comprehensive (CSCs), severity, and sex are associated direct‐to‐CSC prehospital in LVO AIS. Methods Results In this cross‐sectional study, identified consecutive AIS from a prospectively collected multihospital registry throughout the greater Houston area January 2019 June 2020. Primary outcome was CSC compared between men women using modified Poisson regression including age, sex, race or ethnicity, first in‐hospital National Institutes Health Stroke Scale score, travel time, distances closest primary center CSC. Among 503 AIS, 413 (82%) were routed CSCs, comprised 46% study participants. Women older (73 versus 65, P <0.01) presented score (14 12, =0.01). regression, 9% less likely be CSCs (adjusted relative risk [aRR], 0.91 [0.84–0.99], =0.024) nearest ≤10 miles 38% increased chance (aRR, 1.38 [1.26–1.52], <0.001). Conclusions Despite presenting more significant syndromes living within comparable men. Further mechanisms behind disparity is needed.