CircALMS1 Alleviates Pulmonary Microvascular Endothelial Cell Dysfunction in Pulmonary Hypertension

• DOI: 10.1161/jaha.123.031867
• Publication Date: 2024-03-18T11:03:01Z
• Authors: Xiaoyi Hu; Yuanyuan Sun; Shang Wang; Hui Zhao; Yaqin Wei; Jiaqi Fu; Yuxia Huang; Wenhui Wu; Jinling Li; Jinming Liu; Sugang Gong; Qinhua Zhao; Lan Wang; Rong Jiang; Xiao Song; Ping Yuan
• Keywords: Hypoxia; Circular RNA; Pathogenesis

Circular RNAs can serve as regulators influencing the development of pulmonary hypertension (PH). However, their function in vascular intimal injury remains undefined. Thus, we aimed to identify specifically expressed circular microvascular endothelial cells (PMECs) under hypoxia and PH.