Enhanced Cardiomyocyte NLRP3 Inflammasome‐Mediated Pyroptosis Promotes d ‐Galactose–Induced Cardiac Aging

• DOI: 10.1161/jaha.123.032904
• Publication Date: 2024-07-09T11:57:50Z
• Authors: Wen‐bin Liu; Sui‐sui Wang; Xu Zhang; Ze‐zhi Ke; Xiu‐yun Wen; Jie Zhao; Xiao‐dong Zhuang; Li‐zhen Liao
• Keywords: Pyroptosis

Cardiac aging represents an independent risk factor for aging-associated cardiovascular diseases. Although evidence suggests association between NOD-, LRR-, and pyrin domain-containing protein 3 (NLRP3) inflammasome formation numerous diseases, its role in cardiac remains largely unclear.