Abstract WP282: Association of Very Short Interval Blood Pressure Variability With Stroke

Stroke
DOI: 10.1161/str.55.suppl_1.wp282 Publication Date: 2024-02-01T10:11:28Z
ABSTRACT
Background: While blood pressure variability (BPV) is associated with poor cardiovascular outcomes, the relationship between BPV obtained in a very short interval and stroke unknown. We aim to examine association history of stroke. Hypothesis: Higher likelihood having Methods: A cross-sectional study using 2017-2020 NHANES included 3 consecutive BP measurements taken 60 seconds apart. The average real (ARV) systolic diastolic (AVR-SBP AVR-DBP) was assessed as an absolute difference BP. AVR-SBP AVR-DBP examined by multiple logistic regression. Results: Of 9,693 adult participants, mean±SD age 50±19 years 51% were female. Up 5% (487 patients) had Mean three SBP DBP 120±20 72±12 mmHg, respectively. Median (IQR) ARV-SBP 3.5 (2, 6) mmHg ARV-DBP 2.4 (1.5, 4) mmHg. Patients significantly higher ARV-SBP, but not compared non-stroke patients (mean (95%CI) 11 (9, 13); 0.7, (0.4, 1.1); 0.7 (-0.5, 1.9); 0.1 (-0.2, 0.4)). For every one increase there 4.6% greater odds (OR 1.05 (1.02, 1.07)), while 1.6% for no statistical significance 1.02 (0.98, 1.05)). After adjusting age, gender, race, ethnicity, BMI, 2.8% 1.03 (1.00, 1.05)) ARV - remained non-significant. only who diagnosed at < 50 old, regardless when diagnosed. Conclusions: prior younger than old. Impaired cerebral vasculatures may affect autoregulation stroke, which possibly manifests BPV. Longitudinal cohort studies determine are required.
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