The Prognostic Value of Capillary Glucose Levels in Acute Stroke

• DOI: 10.1161/strokeaha.108.519926
• Publication Date: 2008-12-19T02:40:49Z
• Authors: Blanca Fuentes; José Castillo; Belén San José; Rogelio Leira; Joaquín Serena; José Vivancos; Antonio Dávalos; Antonio Gil Nuñez; José Egido; Exuperio Díez-Te...
• Keywords: Stroke; Acute stroke

Evidence is accumulating regarding the prognostic influence of hyperglycemia in patients with acute ischemic stroke. However, level associated poor outcome unknown. Our objectives were to establish capillary glucose threshold highest predictive accuracy and evaluate its hypothetical value influencing functional by adjusting for other well-known factors stroke.The authors conducted a multicenter, prospective, observational cohort study 476 stroke within less than 24 hours from onset. Capillary finger-prick severity determined on admission 3 times day during first 48 hours. Poor (modified Rankin Scale >2) was evaluated at months.The receiver operating characteristic curves showed maximum any time an area under curve 0.656 (95% CI, 0.592 0.720; P<0.01) pointed 155 mg/dL as optimal cutoff months (53% sensitivity; 73% specificity). This point 2.7-fold increase 1.42 5.24) odds after adjustment age, diabetes, admission, infarct volume, baseline 3-fold risk death (hazard ratio, 3.80; 95% 1.79 8.10).Hyperglycemia >or=155 onset, not only isolated glycemia, independently severity, or age.