Current Status and Time Trends of Oral Anticoagulation Use Among Chinese Patients With Nonvalvular Atrial Fibrillation

• DOI: 10.1161/strokeaha.116.012988
• Publication Date: 2016-06-10T02:53:51Z
• Authors: San-Shuai Chang; Jian-Zeng Dong; Chang-Sheng Ma; Xin Du; Jia-Hui Wu; Ri-Bo Tang; Shi-Jun Xia; Xue-Yuan Guo; Rong-Hui Yu; De-Yong Long; Rong Bai; Nian Liu; Cai-Hua Sang; Chen-Xi Jiang; Xiao-Hui Liu; Jian-Hong Pan; Gregory Y.H. Lip
• Keywords: Stroke; Oral anticoagulant

Reported rates of oral anticoagulation (OAC) use have been low among Chinese patients with atrial fibrillation (AF). With improved awareness, changing guidelines, this situation may be over time. We aimed to explore the current status and time trends OAC in Beijing.We used data set from Atrial Fibrillation Registry (CAFR), a prospective, multicenter, hospital-based registry study involving 20 tertiary 12 nontertiary hospitals Beijing. A total 11 496 AF were enrolled 2011 2014.Seven thousand nine hundred seventy-seven eligible included ancillary study. The proportions 36.5% (2268/6210), 28.5% (333/1168), 21.4% (128/599) for CHA2DS2-VASc scores ≥2, 1, 0, respectively. Persistent AF, history stroke/transient ischemic attack/peripheral embolism, diabetes mellitus, higher body mass index, hospital management factors positively associated use, whereas older age, previous bleeding, hypercholesterolemia, established coronary artery disease negatively use. Among CHADS2 ≥2 proportion increased 31.3% 64.5% 30.2% 57.7%, respectively, 2014. Variation was substantial different hospitals.An improvement Beijing is observed recent years although only score received OAC. However, variations between large, suggesting that better education awareness are needed improve efforts stroke prevention patients.URL: http://www.chictr.org.cn/showproj.aspx?proj=5831. Unique identifier: ChiCTR-OCH-13003729.