Stroke Incidence and Outcomes in Northeastern Greece

• DOI: 10.1161/strokeaha.117.019524
• Publication Date: 2018-01-15T10:05:22Z
• Authors: Georgios Tsivgoulis; Athanasia Patousi; Maria Pikilidou; Theodosis Birbilis; Aristeidis H. Kat...; Michalis Mantatzis; Aristeidis Asimis; Nikolaos Papanas; Panagiotis Skendros; Aikaterini Terzoudi; Aikaterini Karamanli; Ioannis Kouroumic...; Pantelis Zebekakis; Efstratios Maltezos; Charitomeni Piper...; Konstantinos Vadi...; Ioannis Heliopoulos
• Keywords: Stroke

Background and Purpose— Data are scarce on both stroke incidence rates outcomes in Greece rural areas particular. We performed a prospective population-based study evaluating the of first-ever Evros prefecture, region total 147 947 residents located North Eastern Greece. Methods— Adult patients with were registered during 24-month period (2010–2012) followed up for 12 months. To compare our that observed other studies, we standardized rate data according to European Standard Population, World Health Organization, Segi population. also applied criteria quality proposed by Monitoring Trends Determinants Cardiovascular Disease project. Stroke diagnosis classification using Organization basis neuroimaging autopsy data. Results— prospectively documented 703 cases (mean age: 75±12 years; 52.8% men; ischemic stroke: 80.8%; intracerebral hemorrhage: 11.8%; subarachnoid 4.4%; undefined: 3.0%) follow-up time 119 805 person-years. The unadjusted Population–adjusted incidences all strokes 586.8 (95% confidence interval [CI], 543.4–630.2) 534.1 CI, 494.6–573.6) per 100 000 person-years, respectively. stroke, hemorrhage, hemorrhage 474.1 435–513), 69.3 54–84), 25.9 17–35) corresponding person-years 425.9 390.9–460.9), 63.3 49.7–76.9), 25.8 16.7–34.9) overall 28-day case fatality was 21.3% 18.3%–24.4%) higher hemorrhagic than (40.4%, 95% 31.3%–49.4% versus 16.2%, 13.2%–19.2%). Conclusions— This is largest date documenting one highest ever reported South Europe, highlighting need efficient prevention treatment strategies Northeastern