Lung Function and Inflammatory Responses in Healthy Young Adults Exposed to 0.06 ppm Ozone for 6.6 Hours

• DOI: 10.1164/rccm.201011-1813oc
• Publication Date: 2011-01-08T03:23:31Z
• Authors: Chong S. Kim; Neil E. Alexis; Ana G. Rappold; Howard Kehrl; Milan J. Hazucha; John C. Lay; Mike T. Schmitt; Martin Case; Robert B. Devlin; David B. Peden; David Diaz-Sanchez
• Keywords: Adult; Inflammation; Male; Air Pollutants; Inhalation Exposure; Time Factors; Neutrophils; Reverse Transcriptase Polymerase Chain Reaction; Vital Capacity; Respiratory Function Tests; 3. Good health; Young Adult; Ozone; Reference Values; Spirometry; Forced Expiratory Volume; Humans; Female; Exercise; Lung; Glutathione Transferase

Exposure to ozone causes a decrease in spirometric lung function and an increase airway inflammation healthy young adults at concentrations as low 0.08 ppm, close the National Ambient Air Quality Standard for ground level ozone.