FEV1 Decline in Patients with Chronic Obstructive Pulmonary Disease Associated with Biomass Exposure

• DOI: 10.1164/rccm.201404-0720oc
• Publication Date: 2014-08-30T05:55:57Z
• Authors: Alejandra Ramírez...; Raul H. Sansores; Roger H. Quintana...; Monica Velázquez-...; Rafael J. Hernand...; Candelaria Sánche...; Alejandra Velazqu...; Fernando Flores-T...
• Keywords: Male; Smoking; Environmental Exposure; 3. Good health; Cohort Studies; Pulmonary Disease, Chronic Obstructive; 03 medical and health sciences; 0302 clinical medicine; Forced Expiratory Volume; Smoke; Humans; Female; Biomass; Aged

Biomass exposure is an important risk factor for chronic obstructive pulmonary disease (COPD). However, the time-course behavior of FEV1 in subjects exposed to biomass unknown.We undertook this study determine rate decline biomass.Pulmonary function was assessed every year a Mexican cohort patients with COPD associated or tobacco during 15-year follow-up period.The mean significantly lower group (BE-COPD) than smoke (TS-COPD) (23 vs. 42 ml, respectively; P < 0.01). Of TS-COPD group, 11% were rapid decliners, whereas only one decliner found BE-COPD group; 69 and 21% smokers versus 17 83% slow decliners sustainers, respectively. A higher both as % predicted milliliters predictive TS-COPD, reversibility bronchodilator groups when adjusted by FEV1% milliliters.In slower shows more homogeneous over time comparison smokers. The rare feature biomass-induced airflow limitation.