In-Hospital Mortality after Surgical Lung Biopsy for Interstitial Lung Disease in the United States. 2000 to 2011

• DOI: 10.1164/rccm.201508-1632oc
• Publication Date: 2015-12-09T12:01:05Z
• Authors: John P. Hutchinson; Andrew W. Fogarty; Tricia M. McKeever; Richard B. Hubbard
• Keywords: Lung biopsy

Rationale: Surgical lung biopsy can help to determine a specific diagnosis in interstitial disease but has associated risks. Most currently available mortality data are derived from case series and may not be generalizable broader populations.Objectives: To assess in-hospital after surgical for national secondary care dataset the United States.Methods: Data were obtained 2000–2011 Nationwide Inpatient Sample. Cases identified using International Classification of Diseases codes biopsies. Lung resections cases cancer excluded. Weighted used estimate numbers biopsies nationwide mortality, multivariable logistic regression was adjust sex, age, geographic region, comorbidity, type operation, provisional diagnosis.Measurements Main Results: We estimated there around 12,000 performed annually States, two-thirds which electively. In-hospital 1.7% elective procedures significantly higher nonelective (16.0%). Male increasing open surgery, idiopathic pulmonary fibrosis or connective tissue disease–related risk factors increased mortality.Conclusions: is just under 2% procedures. Identified death should taken into account when counseling patients on whether pursue histologic diagnosis.