High-Dose Inhaled Nitric Oxide in Acute Hypoxemic Respiratory Failure Due to COVID-19: A Multicenter Phase II Trial

• DOI: 10.1164/rccm.202304-0637oc
• Publication Date: 2023-09-29T18:01:32Z
• Authors: Raffaele Di Fenza; Naman S. Shetty; Stefano Gianni; Vibhu Parcha; Valentina Giammatteo; Bijan Safaee Fakhr; Daniel Tornberg; Olof Wall; Piotr Harbut; Peggy S. Lai; Jonathan Z. Li; Sabrina Paganoni; Stefano Cenci; Ariel L. Mueller; Timothy T. Houle; Oluwaseun Akeju; Edward A. Bittner; Somnath Bose; Louie K. Scott; Ryan W. Carroll; Fumito Ichinose; Magnus Hedenstierna; Pankaj Arora; Lorenzo Berra; Caio C. Araujo Mo...; Lauren E. Gibson; Takamitsu Ikeda; Eizo Marutani; Yusuke Miyazaki; Anna Fischbach; Lisa Traeger; Martin I. Capriles; Eduardo Diaz Delgado; Grant M. Larson; Roberta Ribeiro D...; Carolyn La Vita; Binglan Yu; Maurizio F. Cereda; Nattaly Greene; Paula Restrepo; James P. Flynn; James Regan; Riccardo Pinciroli; Elizabeth I. Caskey; Kimberley Hutchinson; N. Stuart Harris; Josanna Rodriguez...; Marvin G. Chang; Jacob Wideaus; Matilda Widaeus; Kambiz Shahgaldi; Karl Hagman; Garima Arora; Robert Johnson
• Keywords: 2019-20 coronavirus outbreak

The effects of high-dose inhaled nitric oxide on hypoxemia in coronavirus disease (COVID-19) acute respiratory failure are unknown.