VFMA: Topographic Analysis of Sensitivity Data From Full-Field Static Perimetry

• DOI: 10.1167/tvst.4.2.14
• Publication Date: 2016-06-22T22:31:36Z
• Authors: Richard G. Weleber; Travis B. Smith; Dawn Peters; Elvira N. Chegarnov; Scott P. Gillespie; Peter J. Francis; Stuart K. Gardiner; Jens Paetzold; Janko Dietzsch; Ulrich Schiefer; Chris A. Johnson
• Keywords: Repeatability; Visual inspection

To analyze static visual field sensitivity with topographic models of the hill vision (HOV), and to characterize several function indices derived from HOV volume.A software application, Visual Field Modeling Analysis (VFMA), was developed for perimetry data visualization analysis. Three-dimensional were generated 16 healthy subjects 82 retinitis pigmentosa patients. Volumetric indices, which are measures quantity comparable regardless perimeter test pattern, investigated. Cross-validation, reliability, cross-sectional analyses performed assess this methodology compare volumetric conventional mean deviation. Floor effects evaluated by computer simulation.Cross-validation yielded an overall R2 0.68 index agreement 0.89, consistent among subject groups, indicating good accuracy. in terms test-retest variability discriminability groups. Simulated floor did not negatively impact repeatability any index, but large changes altered regional indices.VFMA is effective tool clinical research data. Topographic aid defects, topographically quantify magnitude extent sensitivity.VFMA assists interpretation perimetric device location pattern. suitable diagnosis, monitoring loss, patient counseling, endpoints therapeutic trials.