Subgenual Cingulate Cortex Volume in First-Episode Psychosis

• DOI: 10.1176/ajp.156.7.1091
• Publication Date: 2022-07-29T12:19:12Z
• Authors: Yoshio Hirayasu; Martha E. Shenton; Dean F. Salisbury; Jun Soo Kwon; Cynthia G. Wible; Iris A. Fischer; Deborah Yurgelun-...; Carlos Zarate; Ron Kikinis; Ferenc A. Jolesz; Robert W. McCarley
• Keywords: Cingulate cortex; Depression

Gray matter volume and glucose utilization have been reported to be reduced in the left subgenual cingulate of subjects with familial bipolar or unipolar depression. It is unclear whether these findings are secondary recurrent illness part a familial/genetic syndrome. The authors' goal was clarify findings.Volumetric analyses were performed by using magnetic resonance imaging 41 patients experiencing their first episode affective disorder schizophrenia 20 normal comparison subjects.The who had family history smaller than that no subjects. Patients did not differ from volume.Left abnormalities present at hospitalization for psychotic disorder.