Long-Term Cannabis Use and Cognitive Reserves and Hippocampal Volume in Midlife

• DOI: 10.1176/appi.ajp.2021.21060664
• Publication Date: 2022-03-08T08:00:36Z
• Authors: Madeline H. Meier; Avshalom Caspi; Annchen R. Knodt; Wayne Hall; Antony Ambler; HonaLee Harrington; Sean Hogan; Renate M. Houts; Richie Poulton; Sandhya Ramrakha; Ahmad R. Hariri; Terrie E. Moffitt
• Keywords: Cognitive reserve

Cannabis use is increasing among midlife and older adults. This study tested the hypotheses that long-term cannabis associated with cognitive deficits smaller hippocampal volume in midlife, which important because are risk factors for dementia.