Dahi Containing Probiotic Lactobacillus Acidophilus and Lactobacillus Casei Has a Protective Effect against Salmonella Enteritidis Infection in Mice

• DOI: 10.1177/039463200802100428
• Publication Date: 2017-01-12T17:27:30Z
• Authors: S. Jain; H. Yadav; P.R. Sinha; Y. Naito; F. Marotta
• Keywords: Salmonella enteritidis; Lactobacillus casei

Salmonella enteritidis infection has received attention during recent years owing to its high prevalence worldwide. In the present study, protective effect of probiotic dahi (curd) supplemented with Lactobacillus acidophilus and L. casei against in mice is investigated. Seven days pre-feeding significantly increased anti- S. sIgA (secretary IgA) antibodies lymphocyte proliferation infected mice. IL-2, IL-6 IFNγ production were supernatant cultured splenocytes collected from pre-fed dahi, while IL-4 levels not changed significantly. Moreover, activities β-galactosidase β-glucuronidase, counts intestine, liver spleen decreased, whereas total lactobacilli faeces dahi. Pre-feeding for 7 was more effective than 2 pre-feeding. Thus, results indicate that, ameliorated by stimulating specific non-specific immune response. Above all, it lowered colonization gastrointestinal tract as well translocation enteritidis.