Methylphenidate-Induced Acute Orofacial and Extremity Dyskinesia

• DOI: 10.1177/0883073812449905
• Publication Date: 2012-07-13T16:21:01Z
• Authors: Ayse Esra Yilmaz; Ahsen Donmez; Emel Orun; Tugba Tas; Bunyamin Isık; Fatma Mujgan Sonmez
• Keywords: Orofacial Pain

Methylphenidate is a short-acting stimulant. In this article, the authors report 7-year-old male patient who presented with orofacial and limb dyskinesia after his first dose of methylphenidate treatment for diagnosis attention-deficit/hyperactivity disorder; he was also receiving sodium valproate epilepsy. Orofacial appeared 5 hours administration, persisted 10 hours, had completely resolved within 2 days. Although commonly reported side effect, to authors’ knowledge only second case develop both in acute period methylphenidate. This emphasize potential effects methylphenidate, individual differences drug sensitivities, drug–receptor interactions via different mechanisms.