Prediction of Preload Responsiveness by the Change in Carotid Peak Velocity Variation with Tidal Volume Challenge

• DOI: 10.1177/09760016251328519
• Publication Date: 2025-04-12T10:13:26Z
• Authors: Koteshwar Rao Mad...; Senthilkumar Raja...; Ramakrishnan Naga...; Ramesh Venkataraman; Vignesh Chandrase...
• Keywords: Preload; Variation (astronomy)

Background and Aims: Tidal volume (TV) challenge was shown to improve the reliability of pulse pressure variation (PPV) in predicting responsiveness. Carotid peak velocity (CPV) has similar potential predict This study compared performance CPV PPV responsiveness following a TV challenge. Methodology: In patients with haemodynamic instability, baseline were measured at 6 ml/kg (CPV6 PPV6) 8 (CPV8 PPV8), changes (∆CPV (6–8) ∆PPV (6–8)) recorded. The then reduced ml/kg. After fluid bolus (6 ml/kg), change cardiac output (CO) trans thoracic echocardiogram by more than 15% considered response. Results: Among 42 studied, mean PPV6 18.94 ± 5.61 76.40 13, respectively, whereas PPV8 CPV8 23 6.06 79.86 13.5. Mean ∆CPV 4.15 1.4 3.61 1.6. absolute after predicted AUROC (with 95% CIs) 0.71 (95% CI: 0.55–0.88), 0.84 0.6–0.95), respectively. Conclusions: prediction is