Cerebellar Gray Matter Density in Females With ADHD Combined Type: A Cross-Sectional Voxel-Based Morphometry Study

• DOI: 10.1177/1087054710366421
• Publication Date: 2011-04-14T02:36:14Z
• Authors: Luis Guillermo Al...; Josefina Ricardo-...; Lázaro Barajas De...; Hugo Prado Alcántara; Reyna Beatriz Mar...; David Ávila Acosta; Antonio Fernández...
• Keywords: Voxel-based morphometry; Cerebellar hemisphere; Gray (unit); Abnormality; Right hemisphere; Cross-sectional study

MRI studies have shown a decreased cerebellum volume in individuals with ADHD. However, most of these were conducted male children, many whom medicated stimulants. As such, unmedicated, non-White girls are underrepresented such studies.The aim the present study was to compare density gray matter (GM) cerebellar hemisphere between female adolescents, and adults diagnosed ADHD combined type (ADHD-C) healthy controls.MRIs performed on 11 Hispanic unmedicated ADHD-C children (6-10 years old), 8 adolescents (14-17 10 (25-35 respective controls. Image processing statistical analyses by Voxel Based Morphometry using DARTEL algorithm improve spatial normalization.Reduced GM located right found ADHD-C.These findings suggest that there is an anatomical abnormality from childhood adulthood.