The Role of msa in Staphylococcus aureus Biofilm Formation

• DOI: 10.1186/1471-2180-8-221
• Publication Date: 2008-12-16T19:14:22Z
• Authors: Karthik Sambantha...; Antony Schwartz; Vijayaraj Nagarajan; Mohamed O Elasri
• Keywords: Human pathogen

Abstract Background Staphylococcus aureus is an important pathogen that forms biofilms. The global regulator sarA essential for biofilm formation. Since the modulator of ( msa ) required full expression and regulates several virulence factors, we examined capacity mutant to form biofilm. Results We found mutation results in reduced formed a weak unstable able adhere surfaces begins but fails mature indicating defect accumulation stage not primary adhesion. Conclusion gene plays role development which likely due its modulating . This finding significant because it identifies new