Discordance in diagnosis of osteoporosis using spine and hip bone densitometry

• DOI: 10.1186/1472-6823-5-3
• Publication Date: 2005-03-12T07:15:51Z
• Authors: Alireza Moayyeri; Akbar Soltani; Nasibeh Khaleghne...; Mohsen Sadatsafavi; Arash Hossein-neghad; Bagher Larijani
• Keywords: Densitometry; Concordance

BACKGROUND: Diagnostic discordance for osteoporosis is the observation that T-score of an individual patient varies from one key measurement site to another, falling into two different diagnostic categories identified by World Health Organization (WHO) classification system. This study was conducted evaluate presence and risk factors this phenomenon in a large sample Iranian population. METHODS: Demographic data, anthropometric measurements, were derived database on 4229 patients referred community-based outpatient testing center 2000 2003. Dual-energy X-ray absorptiometry (DXA) performed L1-L4 lumbar spine total hip all cases. Minor defined as present when difference between sites no more than WHO class. Major osteoporotic other normal. Subjects with incomplete data excluded. RESULTS: In 4188 participants (3848 female, mean age 53.4 +/- 11.8 years), major discordance, minor concordance T-scores seen 2.7%, 38.9% 58.3%, respectively. multivariate logistic regression analysis, older age, menopause, obesity, belated menopause recognized hormone replacement therapy protective factor against discordance. CONCLUSION: The high prevalence may lead problems interpretation densitometry results some patients. should be regarded real prevalent finding physicians develop particular strategy approaching these