Functional status and quality of life 12 months after discharge from a medical ICU in healthy elderly patients: a prospective observational study

• DOI: 10.1186/cc10121
• Publication Date: 2011-04-05T06:13:55Z
• Authors: Emilio Sacanella; Joan Manel Pérez-...; Josep Maria Nicolás; Ferran Masanés; Marga Navarro; Pedro Castro; Alfonso López-Soto
• Keywords: Aged, 80 and over; Male; Time Factors; Critical Care; Research; Critical Care and Intensive Care Medicine; Survival Analysis; Patient Discharge; 3. Good health; 03 medical and health sciences; 0302 clinical medicine; Activities of Daily Living; Outcome Assessment, Health Care; Quality of Life; Humans; Female; Prospective Studies; Aged; Follow-Up Studies

Abstract Introduction Long-term outcomes of elderly patients after medical ICU care are little known. The aim the study was to evaluate functional status and quality life 12 months discharge from a ICU. Methods We prospectively studied 112/230 healthy (≥65 years surviving at least discharge) with full autonomy without cognitive impairment prior entry. main diagnoses admission using Acute Physiology Chronic Health Evaluation III (APACHE III) classification diagnosis length stay scores II, Sepsis-related Organ Failure Assessment (SOFA) OMEGA) were collected. Comprehensive geriatric assessment included presence syndromes application Lawton, Barthel, Charlson Indexes Informant Questionnaire on Cognitive Decline functionality, comorbidity status, respectively. EuroQol-5D assessed life. Data collected baseline, during ward 3, 6 hospital discharge. Paired or unpaired T-tests compared differences between groups (continuous variables), whereas chi-square Fisher exact tests used for comparing dichotomous variables. For variables significant ( P ≤ 0.1) univariate analysis, forward multiple regression analysis performed. Results Only 48.9% (mean age: 73.4 ± 5.5 years) alive showing decrease in (Lawton Barthel Indexes) (EuroQol-5D) baseline < 0.001, all). Multivariate showed higher Index EQ-5D vas be associated factors recovery 0.01, both). Thus, ≥ 60 ≥40 hazard ratio 4.04 (95% CI: 1.58 10.33; = 0.005) 6.1 1.9 19.9; 0.01), Geriatric increased remained significantly follow-up 0.001). Conclusions survival rate is low (49%), although similar most survivors. However, there two-fold increase prevalence syndromes.