Effects of hypertonic saline on a pig model of acute lung injury induced by hydrochloric acid instillation

• DOI: 10.1186/cc8431
• Publication Date: 2010-03-02T07:19:46Z
• Authors: CA Holms; DA Otsuki; M Kahvegian; J Noel-Morgan; C Massoco; DT Fantoni; P Gutierrez; JO Auler
• Keywords: Hypertonic saline; Pulmonary Injury; Inflammatory response

Controversy exists over the possible beneficial effects of hypertonic saline (HS) in pulmonary inflammatory response, particularly neutrophil immunomodulation [1,2]. This study was designed to investigate benefits HS treatment pigs submitted experimental acute lung injury.