Microarray-based gene expression profiles in multiple tissues of the domesticated silkworm, Bombyx mori

• DOI: 10.1186/gb-2007-8-8-r162
• Publication Date: 2007-08-04T18:13:30Z
• Authors: Qingyou Xia; Daojun Cheng; Jun Duan; Genhong Wang; Tingcai Cheng; Xingfu Zha; Chun Liu; Ping Zhao; Fangyin Dai; Ze Zhang; Ningjia He; Liang Zhang; Zhonghuai Xiang
• Keywords: Male; Sex Characteristics; 0303 health sciences; Gene Expression Profiling; Genome, Insect; Oligonucleotides; Method; Bombyx; Salivary Glands; 03 medical and health sciences; Animals; Drosophila; Female; Oligonucleotide Array Sequence Analysis

AbstractWe designed and constructed a genome-wide microarray with 22,987 70-mer oligonucleotides covering the presently known and predicted genes in the silkworm genome, and surveyed the gene expression in multiple silkworm tissues on day 3 of the fifth instar. Clusters of tissue-prevalent and tissue-specific genes and genes that are differentially expressed in different tissues were identified, and they reflect well major tissue-specific functions on the molecular level. The data presented in this study provide a new resource for annotating the silkworm genome.