Pericardial tamponade due to haemorrhagic pericardial effusion as a complication of prasugrel: a case report

• DOI: 10.1186/s12872-016-0338-8
• Publication Date: 2016-08-30T06:40:02Z
• Authors: Fathima Aaysha Cader; M. Maksumul Haq; Sahela Nasrin; Md. Rezaul Karim
• Keywords: Thienopyridine

Striking an adequate balance between bleeding risks and prevention of stent thrombosis can be challenging in the setting percutaneous coronary intervention (PCI) with drug eluting stents (DES) acute myocardial infarction (MI). This is more pronounced patients treated both low molecular weight heparin (LMWH) dual antiplatelet therapy (DAPT). Prasugrel, a second generation thienopyridine potent platelet inhibition capability, associated significant risks. risk often underestimated when prescribing pharmacological agents such as DAPT LMWH, designed to reduce ischaemic events following PCI MI. Life-threatening haemorrhagic pericardial pleural effusions not access site are rare example complications. We report case Bangladeshi male who developed cardiac tamponade resulting from effusion well bilateral effusions, 9 days after DES, while on prasugrel aspirin. He had presented late inferior ST elevation (STEMI), was therefore also given enoxaparin initially. Haemorrhagic fluid were drained, patient discharged comprising aspirin clopidogrel. Following obtuse marginal, which done staged procedure 6 months later, he commenced ticagrelor instead no further complications over 1 year follow up. Non-access this, leading life-threatening. Furthermore, syndromes (ACS) have marked variation their major bleeding. Since mortality, maintaining recurrent ischemia that paramount importance. The use validated scores, careful monitoring or switch lesser may