Predictive efficacy of neutrophil-to-lymphocyte ratio for long-term prognosis in new onset acute coronary syndrome: a retrospective cohort study

• DOI: 10.1186/s12872-020-01773-x
• Publication Date: 2020-11-30T15:03:48Z
• Authors: Yi Yang; Yanan Xu; Jun Wang; Xueqin Zhai; Haibing Jiang
• Keywords: Angiology; Mace

Abstract Background Inflammation is involved in the pathogenesis and progression of coronary artery diseases (CADs), including acute syndrome. The neutrophil-to-lymphocyte ratio (NLR) has been identified as a novel marker pro-inflammatory state. We aimed to evaluate predictive efficacy NLR for prognosis patients with new-onset ACS. Methods retrospectively included consecutive ACS treated emergency angiography. was measured at baseline analyzed by tertiles. severity lesions evaluated Gensini score. Correlations CAD incidence major adverse cardiovascular (MACEs) during follow-up were determined. Results Overall, 737 included. positively correlated assessed score ( P < 0.05). During period (mean, 43.49 ± 23.97 months), 65 MACEs occurred. No significant association detected between risk either Kaplan–Meier or Cox regression analysis. Multivariable logistic analysis showed that higher independently associated lesion (1st tertile vs. 3rd hazard [HR]: 0.527, 0.001, 2nd HR: 0.474, = 0.025). Conclusions may be disease but not outcomes Ethics Approval Number 2019XE0208