Plasma atherogenic indices are independent predictors of slow coronary flow

• DOI: 10.1186/s12872-021-02432-5
• Publication Date: 2021-12-20T06:02:34Z
• Authors: Abdulmecit Afsin; Hakan Kaya; Arif Suner; Kader Eliz Uzel; Nurbanu Bursa; Yusuf Hosoglu; Fethi Yavuz; Ramazan Asoglu
• Keywords: Dyslipidemia; Pathophysiology

Abstract Background Although the pathophysiology of coronary slow flow (CSF) has not been fully elucidated, emerging data increasingly support potential role for subclinical diffuse atherosclerosis in etiology CSF. We aimed to investigate relationship between atherogenic indices and Methods 130 patients with CSF diagnosed according Thrombolysis Myocardial Infarction (TIMI)-frame count (TFC) method controls who had normal (NCF) were included this retrospective study. Atherogenic (atherogenic index plasma [AIP], Castelli risk I II [CRI-I II]) calculated using conventional lipid parameters. Results The logistic regression analyses demonstrated that AIP (OR, 5.463; 95% confidence interval [CI], 1.357–21.991; p = 0.017) CRI-II 1.624; CI, 1.138–2.319; 0.008) independent predictors Receiver operating characteristic analysis showed optimal cutoff value predict occurrence was 0.66 (sensitivity, 59%; specificity, 73%; area under curve [AUC], 0.695; < 0.001) 3.27 60%; 79%; AUC, 0.726; 0.001). Conclusions levels Prospective studies larger cohorts may elucidate dyslipidemia