Triglyceride glucose index exacerbates the risk of future cardiovascular disease due to diabetes: evidence from the China Health and Retirement Longitudinal Survey (CHARLS)

• DOI: 10.1186/s12872-022-02673-y
• Publication Date: 2022-05-21T13:04:23Z
• Authors: Zixiang Ye; Enmin Xie; Siqi Jiao; Yanxiang Gao; Peizhao Li; Yimin Tu; Ziyu Guo; Qing Li; Yaxin Wu; Xiaozhai Yu; Yike Li; Changan Yu; Jingyi Ren; Jingang Zheng
• Keywords: Dyslipidemia; Longitudinal Study; Angiology; Subgroup analysis

We aimed to investigate the effect of triglyceride glucose (TyG) index on association between diabetes and cardiovascular disease (CVD).Data from 6,114 individuals were extracted analyzed China Health Retirement Longitudinal Survey (CHARLS) 2011 2018. Logistic regression analyses conducted assess relationship CVD across various TyG groups. The statistical method subgroup analysis was used determine correlation for each group by sex, history hypertension dyslipidemia, smoking, drinking.Diabetes positively associated with risk after adjustment in 2011(odds ratio (OR) 1.475, 95% CI 1.243-1.752, P < 0.001). There a gradient increase OR new-onset 2018 due at baseline value based fully adjusted model (P trend 0.05). ORs 1.657 (95% 0.928-2.983, = 0.098), 1.834(95% 1.064-3.188, 0.037) 2.234(95% 1.349-3.673, 0.006) T1, T2 T3 respectively. increasing still existed among those nondrinkers analysis.Elevated strengthens mellitus middle-aged elderly Chinese adults.