The usefulness of C-reactive protein and neutrophil-to-lymphocyte ratio for predicting the outcome in hospitalized patients with liver cirrhosis

• DOI: 10.1186/s12876-015-0378-z
• Publication Date: 2015-10-23T15:29:38Z
• Authors: Jung Hyun Kwon; Jeong Won Jang; Young Woon Kim; Sung Won Lee; Soon Woo Nam; Dongwook Jaegal; Seungok Lee; Si Hyun Bae
• Keywords: Hepatic Encephalopathy; Spontaneous bacterial peritonitis

The role of clinical parameters such as systemic inflammatory response syndrome (SIRS) criteria in predicting the infection remains unclear cirrhosis patients. aim was to evaluate usefulness markers including C-reactive protein (CRP) and neutrophil-to-lymphocyte ratio (NLR) for diagnosis outcomes hospitalized cirrhotic study included 184 patients consecutively from 2011 2012. presence overt survival evaluated. CRP concentration, NLR, Model End-Stage Liver Disease (MELD) score SIRS were assessed. main cause admission uncontrolled ascites (36.4 %), followed by varix bleeding (23.9 hepatic encephalopathy (13.6 %). Fifty-eight (31.5 %) had during hospitalization thirty-two (17.4 expired follow up period (median 38 months). Ninety-two (52.2 fulfilled among them, only 32 (38.5 infection. For diagnose infection, baseline concentration a significant factor compared (odds 1.202, P = 0.003). one-month short-term survival, MELD score, NLR WBC count factors but Child-Pugh class C patients, an independent factor. indicator useful predictor 1-month particularly Child–Pugh This suggests that can help identify at risk unfavorable outcomes.