Clinical Frailty Scale (CFS) reliably stratifies octogenarians in German ICUs: a multicentre prospective cohort study

• DOI: 10.1186/s12877-018-0847-7
• Publication Date: 2018-07-13T00:49:41Z
• Authors: Johanna M. Muessig; Amir M. Nia; Maryna Masyuk; Alexander Lauten; Anne Lena Sacher; Thorsten Brenner; Marcus Franz; Frank Bloos; Henning Ebelt; Stefan J. Schaller; Kristina Fuest; Christian Rabe; Thorben Dieck; Stephan Steiner; Tobias Graf; Rolf A. Jánosi; Patrick Meybohm; Philipp Simon; Stefan Utzolino; Tim Rahmel; Eberhard Barth; Michael Schuster; Malte Kelm; Christian Jung
• Keywords: Male; Critical Care; Medizin; 610; 310; 03 medical and health sciences; 610 Medical sciences Medicine; 0302 clinical medicine; Risk Factors; Germany; Humans; ddc:610; Intensive care outcome; Hospital Mortality; Prospective Studies; Retrospective Studies; Aged, 80 and over; ddc:610; Frailty; VIP1; RC952-954.6; 3. Good health; Hospitalization; Intensive Care Units; Geriatrics; Multivariate Analysis; Quality of Life; Female; Clinical frailty scale; Research Article

In intensive care units (ICU) octogenarians become a routine patients group with aggravated therapeutic and diagnostic decision-making. Due to increased mortality reduced quality of life in this high-risk population, medical decision-making fortiori requires an optimum risk stratification. Recently, the VIP-1 trial prospectively observed that clinical frailty scale (CFS) performed well ICU overall-survival short-term outcome prediction. However, it is known healthcare systems differ 21 countries contributing trial. Hence, our main focus was investigate whether CFS usable for stratification admitted diversified high tech German ICUs. This multicentre prospective cohort study analyses very old 20 ICUs as sub-analysis Three hundred eight 80 years age or older consecutively participating CFS, cause admission, APACHE II, SAPS II SOFA scores, use resources ICU- 30-day were recorded. Multivariate logistic regression analysis used identify factors associated mortality. Patients had median 84 [IQR 82–87] mean 4.75 (± 1.6 standard-deviation) points. More than half (53.6%) classified frail (CFS ≥ 5). ICU-mortality 17.3% 31.2%. The admission (planned vs. unplanned), (OR 5.74) 1.44 per point increase) independent predictors survival. easy determinable valuable tool prediction survival octogenarians, thus, may facilitate givers Germany. retrospectively registered on ClinicalTrials.gov (ID: NCT03134807 ) May 1, 2017.