“Late for testing, early for antiretroviral therapy, less likely to die”: results from a large HIV cohort study in China, 2006–2014

• DOI: 10.1186/s12879-018-3158-x
• Publication Date: 2018-06-12T21:18:42Z
• Authors: Houlin Tang; Yurong Mao; Weiming Tang; Jing Han; Juan Xu; Jian Li
• Keywords: Medical microbiology

Timely HIV testing and initiation of antiretroviral therapy are two major determinants survival for HIV-infected individuals. Our study aimed to explore the trend late HIV/AIDS diagnoses assess factors associated with these in China between 2006 2014. We used data from Chinese Comprehensive Response Information Management System (CRIMS). All individuals who tested positive 2014 were at least 15 years age included. A diagnosis was defined as an instance which individual diagnosed having AIDS or WHO stage 3 4 HIV/AIDS, had a CD4 cell count less than 200 cells/mm3 time diagnosis. Among 528,234 (≥15 old) newly 2014, 179,700 (34.0%) people considered have received diagnoses. The rate decreased 33.9% 29.7% (P < 0.01). Late more likely be found among those 45–54 old (adjusted odds ratio [aOR]: 3.25, 95% confidence interval [CI]: 3.17–3.34) 55+ (OR: 2.94, CI: 2.86–3.02), male (aOR: 1.15, 1.13,1.17), employed farmer rural laborer 1.13, 1.11–1.14), infected through blood plasma transfusion 4.18, 4.02, 4.35), hospitals 1.17, 1.19), Han ethnicity 1.30, 1.28, 1.32), married 1.12, 1.11,1.13). Of living (PLHIV) diagnoses, 7.4%(8637) 46.1%(28,462) ultimately died without receiving within year diagnosis, respectively. large proportion receive this has witnessed slight decline recent years. Expanded is needed increase early should recommended all possible reduce AIDS-related death.