Treponema pallidum infection predicts sexually transmitted viral infections (hepatitis B virus, herpes simplex virus-2, and human immunodeficiency virus) among pregnant women from rural areas of Mwanza region, Tanzania

• DOI: 10.1186/s12884-019-2567-1
• Publication Date: 2019-10-30T20:44:43Z
• Authors: Gilbert Ng’wamkai; Kalista V. Msigwa; Damas Chengula; Frank Mgaya; Clotilda Chuma; Betrand Msemwa; Vitus Silago; Mtebe Majigo; Stephen E. Mshana; Mariam M. Mirambo
• Keywords: Serostatus; Hepatitis B

Abstract Background Sexually transmitted infections (STIs) is a global health problem with increased risk and morbidities during pregnancy. This study investigated the magnitude of viral STIs among pregnant women from three rural hospitals/clinics providing antenatal care in Mwanza region, Tanzania. Methods Between February May 2018, total 499 were enrolled tested for Human immunodeficiency virus (HIV), Herpes simplex virus-2 (HSV-2), Hepatitis B (HBV) C (HCV) using rapid immunochromatographic tests syphilis non-treponemal treponemal antibody test. Results The median age was 25 (IQR: 22–31) years. Seventy eight (15.6, 95% CI: 12–18) had at least one sexually infection. Specific prevalence HIV, HBV, HCV, HSV-2 IgG IgM found to be 25(5.0%), 29(5.8%), 2(0.4%), 188(37.7%) 24(4.8%), respectively. odds having infection significantly high positive T. pallidum serostatus (adjusted odd ratio (aOR): 3.24, 95%CI; 1.2–85). By multivariable logistic regression analysis, history predicted seropositivity (aOR: 3.70, 95%CI: 1.43–9.62) while parity 1.23, 1.04–1.46) HBV results 8.63, 2.81–26.45) HIV Conclusion A significant proportion areas region has which independently by serostatus. strengthening expansion ANC screening package include will ultimately reduce hence associated mortalities.