Serum antioxidant micronutrient levels in pre-eclamptic pregnant women in Enugu, south-East Nigeria: a comparative cross-sectional analytical study

• DOI: 10.1186/s12884-020-03081-w
• Publication Date: 2020-07-06T12:03:44Z
• Authors: Joseph Tochukwu E...; Cyril Chukwudi Dim; Emmanuel Onyebuch...; Nympha Onyinye Enebe; Ijeoma Angela Meka; Kingsley Chukwu O...; George Uchenna Eleje; Uchenna Ifeanyi N...
• Keywords: Cross-sectional study

Abstract Background Pre-eclampsia is a common obstetric complication of pregnancy in Nigeria, and oxidative stress has been implicated its aetiopathogenesis. Despite this fact, there paucity information regarding the serum antioxidant micronutrient status pre-eclamptic Nigerian women. The objective was to determine mean levels some trace elements (copper, zinc, selenium, magnesium, manganese) pregnant women compare with that healthy Enugu, South-Eastern, Nigeria. Methods A cross-sectional analytical study carried out at Obstetrics Gynaecology department University Teaching Hospital Ituku-Ozalla, Enugu. Using atomic absorption spectrophotometry, sera 81 matched controls were analyzed for micronutrients. Both descriptive inferential analysis performed using statistical package social sciences (SPSS) version 21.0 P value < 0.05 considered be statistically significant. Results copper, magnesium found significantly lower group when compared ( p 0.05). zinc manganese did not differ between two groups > All micro-nutrients studied vary by category pre-eclampsia (with or without severity findings) except which findings those = 0.043). Conclusions among pre-eclamptics their normal controls. Low may have contributed incidence our environment.