Epidemiology of ossification of the spinal ligaments and associated factors in the Chinese population: a cross-sectional study of 2000 consecutive individuals

• DOI: 10.1186/s12891-019-2569-1
• Publication Date: 2019-05-25T08:02:28Z
• Authors: Haifeng Liang; Guobing Liu; Shunyi Lu; Shuguang Chen; Dongjie Jiang; Hongcheng Shi; Qinming Fei
• Keywords: Hyperostosis

The epidemiology and cause of ossification the spinal ligaments (OSL) remains obscure. To date, there is no study that comprehensively evaluates prevalence, distribution, concomitance each type OSL by CT among general Chinese population. We therefore aimed to investigate epidemiological characteristics using whole spine in population examine factors correlate with presence OSL.Ossification posterior longitudinal ligament (OPLL), ligamentum flavum (OLF), anterior (OALL), nuchal (ONL), diffuse idiopathic skeletal hyperostosis (DISH) were evaluated from subjects who underwent PET/CT for purpose cancer screening our hospital. Prevalence, reviewed. Logistic regression analysis was performed identify risk OSL.A total 2000 (1335 men 665 women) included. prevalence rate cervical OPLL (C-OPLL) 4.1%, thoracic (T-OPLL) 2.25%, lumbar (L-OPLL) 0.8%, OLF (T-OLF) 37.65%, (L-OLF) 1.45%, ONL 31.5%, DISH 3.85%. most commonly involved level C5 C-OPLL, T1 T-OPLL, T10 T-OLF, T8/9 OALL. 21% C-OPLL had 44% 38% T-OPLL 53% L-OPLL 56% T-OLF. average age OSL-positive significantly higher than OSL-negative subjects. results multiple revealed males a strong association (odds ratio, 3.15; 95% confidence interval, 1.27-7.78; P = 0.013).The revealed. Tandem not uncommon people OSL. There high incidence multiple-regional spine. Approximately half coexist For patients clinical symptoms induced OPLL, thorough evaluation recommended.