The role of cerebrospinal fluid cross-section area ratio in the prediction of dural ossification and clinical outcomes in patients with thoracic ossification of ligamentum flavum

• DOI: 10.1186/s12891-021-04574-1
• Publication Date: 2021-08-17T10:03:50Z
• Authors: Jiliang Zhai; Shigong Guo; Yu Zhao; Chunxu Li; Tong Niu
• Keywords: Cerebrospinal fluid cross-section area ratio; Research; Ossification, Heterotopic; Diseases of the musculoskeletal system; Decompression, Surgical; Thoracic Vertebrae; 3. Good health; Dural ossification; 03 medical and health sciences; Ossification of the ligamentum flavum; Ligamentum Flavum; Treatment Outcome; 0302 clinical medicine; RC925-935; Osteogenesis; Cerebrospinal fluid leakage; Cross-sectional area; Humans; Retrospective Studies

Abstract Background It is imperative to preoperatively distinguish dural ossification (DO) and thus anticipate the risks outcome of surgery for patients with ligamentum flavum (OLF). However, studies have disagreed as efficacy radiographic signs or factors predict DO surgical outcome. In additon, association between cerebrospinal fluid cross-section area ratio (CCAR) clinical had not been reported. The purpose this study was analyse CCAR its role in prediction neurological function recovery rate OLF. Methods Fifty-two consecutive OLF, who underwent posterior thoracic decompression fusion September 2012 March 2019 at a single institution, were retrospectively reviewed. Demographic data, DO, CCAR, pre- postoperative modified Japanese Orthopedic Association (mJOA) score recorded. Results There 27 group 25 non-DO group, mean age 57.4 years 53.9 years, respectively. No significant differences found sex, age, segment maximum compression preoperative mJOA two groups. receiver operating characteristic curve showed that value relatively high diagnosis ( P = .000). According three zones defined zone (≤14.3%), (≥44.5%), gray (14.3 44.5%). When CCAR≤14.3%, poor fair, while it good excellent when CCAR≥45.2%. Conclusion diagnostic