Association between platelet to lymphocyte ratio and febrile urinary tract infection after double-J stent removal in children underwent laparoscopic pyeloplasty

• DOI: 10.1186/s12894-025-01808-5
• Publication Date: 2025-05-13T08:31:20Z
• Authors: Xun Lu; Qi Chen; Lixia Wang; Haobo Zhu; Liqu Huang; Jincai Zhou; Yunfei Guo
• Keywords: Pyeloplasty

To evaluate the association between inflammatory biomarkers and prevalence of febrile urinary tract infection (fUTI) after double-J (DJ) stent removal in pediatrics following laparoscopic pyeloplasty (LP). A retrospective study was conducted underwent DJ LP owing to primary ureteropelvic junction obstruction (UPJO) September 2021 November 2024. Baseline characteristics, preoperative data incidence fUTI were documented. The index including neutrophil lymphocyte ratio (NLR), platelet (PLR) systemic immune-inflammation (SII) calculated. results cultured pathogens also identified. univariate multivariate logistic analysis determine potential risk factors removal. predictive value determined by receiver operating characteristic curve (ROC). Overall, 295 patients included study. occurred 22 (7.5%) Patients group younger (P = 0.008) had lower body weight 0.003) compared non-fUTI group. Additionally, showed higher levels platelets neutrophils, associated with lymphocytes. most commonly identified Enterococcus Escherichia coli patients. Multivariate revealed that age (OR 0.978, 95% CI: 0.956-0.999, P 0.047), toilet training status 0.297, 0.109-0.807, 0.017) PLR 1.101, 1.005-1.022, 0.002) for a high an AUC 0.827 sensitivity 90.91% specificity 69.23%. is promising predictor diagnosing before should be closely monitored. Further well-designed prospective cohorts are required future explore cause-and-effect relationship