A prospective interventional study of recombinant human interleukin-11 mouthwash in chemotherapy-induced oral mucositis

• DOI: 10.1186/s12903-022-02348-2
• Publication Date: 2022-07-29T05:02:52Z
• Authors: Hangping Wei; Juan Wei; Xiaofang Dong
• Keywords: Mucositis

This prospective interventional study aimed to evaluate and analyse the efficacy of rhIL-11 mouthwash compared Kangfuxin fluid in treatment blank control prevention oral mucositis (OM) patients receiving chemotherapy.In total, 50 group 62 were included. Subsequently, each was divided into an experimental a group. In group, received recombinant human interleukin-11 (rhIL-11) mouthwash, whereas fluid. still based on routine care, only care. Meanwhile, we observed recorded occurrence grades OM group.Through statistical analysis, results showed that seventh day treatment, more improvement it statistically significant (p = 0.032). The average healing time (3.59 ± 1.927 days) shorter than (4.96 2.421 days; p 0.031). incidence mucositis. No differences found groups 0.175).Our preliminary indicate may be superior option treat OM, especially severe cases, However, there is no advantage prevention.