Oral manifestations associated with inflammatory bowel disease and early endoscopic findings in patients with spondyloarthritis

• DOI: 10.1186/s12903-022-02497-4
• Publication Date: 2022-11-09T04:29:12Z
• Authors: Andrés Alvarado-J...; Katherin Chumacer...; María Rosa Buenahora; Viviana Parra-Izq...; Mónica Monsalve; Ana María Torres; Lorena Chila-Moreno; Cristian Flórez-S...; Alejandro Ramos-C...; Juliette De Avila; Juan Manuel Bello...; Diego Jaimes; Adriana Beltrán-O...; Philippe Chalem-C...; César Pacheco-Tena; Wilson Bautista-M...; Consuelo Romero-S...
• Keywords: Erythema; Chromoendoscopy; Oral mucosa

Abstract Background and aims Spondyloarthritis (SpA) is a group of autoinflammatory disorders, which the primary extra-articular manifestation inflammatory bowel disease (IBD). The oral cavity being part gastrointestinal tract, significantly compromised in IBD, many cases, it first site clinical manifestations IBD. This study aimed to identify changes mucosa associated with onset IBD their association endoscopic/histological findings. Materials methods assessed 80 patients SpA 52 healthy controls. Oral, rheumatological, gastroenterological assessments were performed. ileocolonoscopy was performed via digital magnification chromoendoscopy. statistical analysis consisted Chi-square, Fisher's exact, multiple correspondence discriminant tests. Results From cohort, 63.0% showed lesions ( p = 0.050). These ranged from gingivitis (55.0%, 0.001), aphthous stomatitis (3.8%, 0.091), angular cheilitis (2.6%, 0.200), perioral erythema scaling (1.3%, 0.300). All who presented alterations colonic also had 0.039), specifically gingivitis/aphthous 0.029). Conclusion without present significant signs symptoms. Gingivitis seems be most relevant because its associations early endoscopic histological Clinical relevance An integral approach diagnostic tests that includes evaluations oral, rheumatological tissues may favor timely attention improve patients’ quality life.