Sex hormone levels in females of different ages suffering from depression

• DOI: 10.1186/s12905-021-01350-0
• Publication Date: 2021-05-22T12:02:57Z
• Authors: Rong Lei; Yan Sun; Jiawen Liao; Yuan Yuan; Linlin Sun; Yugeng Liu; Xinyu Yang; Wenyou Ma; Zhenjian Yu
• Keywords: Depression; Age groups

Abstract Background There are only a few studies on sex hormones in females of different ages suffering from depression, and their conclusions not uniform until now. This study aimed to investigate the correlation between severity depression factors such as differences hormone levels ages, exploring variations after treatment. Methods A total 169 with were selected divided into first-episode (91 cases) recurrent (78 groups. Then, basis age, patients young (48 cases, age < 45 years), perimenopausal (20 45–55 elderly groups (23 > 55 years); classified (37 (19 (22 years). The assessed accordance International Classification Diseases mental behavioral disorders. serum progesterone, prolactin, estradiol, testosterone measured, analyzed. Results estradiol level was negatively correlated prolactin positively occupation. found be age. progesterone group significantly higher than those group, regardless first episode or recurrence. Estradiol same depression. However, there no significant difference before Conclusions Sex levels, especially varied among Recurrent also has certain effect females. Not should relapse considered when studying but attention paid whether have used antidepressants sexual hormonal testing.