Atherogenic index of plasma for non-diabetic, coronary artery disease patients after percutaneous coronary intervention: a prospective study of the long-term outcomes in China

• DOI: 10.1186/s12933-022-01459-y
• Publication Date: 2022-02-22T17:31:24Z
• Authors: Yitian Zheng; Chen Li; Jie Yang; Samuel Seery; Yu Qi; Wenyao Wang; Kuo Zhang; Chunli Shao; Yi-Da Tang
• Keywords: Angiology; Mace

Abstract Background Non-diabetic coronary artery disease (CAD) patients are thought to encounter metabolic dysfunction and while these changes may be imperceptible the patient they probably influence outcomes. At present, there is no system support sensing subtle changes, nor an established model for prognoses. The Atherogenic Index of Plasma (AIP) index has already proven useful atherosclerosis although further research needed, especially those without hyperglycemia. Methods This a prospective study 5538 non-diabetic CAD who had received percutaneous intervention (PCI). Participants were assigned one three groups according their AIP index. High cases then compared low major adverse cardiac events (MACE). Restricted cubic spline (RCS) analysis was also conducted investigate interrelations between levels hazard ratios (HR) MACEs. Results Patients with high encountered i.e., higher Body Mass (BMI), Total Cholesterol (TC), Triglycerides (TG), uric acid as well lower HDL-C. Each aforementioned significant p values less than 0.001. There increase in number MACEs group (HR: 1.37, 95% CI 1.04–1.81; = 0.025). A J-shaped RCS curve highlighted change HR after 0.18 juncture (HR per SD: 1.20, 0.96–1.50). Further subgroup supported main findings, all HRs greater one. Conclusion could used prognostics 2 years PCI. relationship ratio appears J-shaped. Although, multi-center studies designed potential should determine value