Severe Plasmodium vivax infection in Korea

• DOI: 10.1186/s12936-017-1684-4
• Publication Date: 2017-01-28T02:31:12Z
• Authors: Jae Hyoung Im; Hea Yoon Kwon; JiHyeon Baek; Seong Wook Park; Areum Durey; Kyung Hee Lee; Moon-Hyun Chung; Jin-Soo Lee
• Keywords: Parasitology; Vivax malaria; Tropical Medicine

Although severe malaria by Plasmodium vivax has been increasingly reported, there are marked variations in the type and rate of complications geographic area. This is possibly because presence concurrent falciparum or bacteraemia, differences underlying immune status among infected subjects. Furthermore, published studies on P. temperate regions limited. The present study investigated Korea, where only occurs. Hence, other compounding factors rare. Additionally, most patients non-immune to this malarial disease.Adults with observed one 860-bed university hospital from January 2006 December 2012 were retrospectively evaluated. Seventeen who had travelled overseas within 6 months before presentation excluded. Severe was diagnosed according World Health Organization criteria. Other also investigated.Two-hundred ten enrolled, which 88 (41.9%) treated as inpatients remainder outpatients. Eleven an intensive care unit; them, five received mechanical ventilation, needed extracorporeal membrane oxygenation therapy (ECMO) additionally. identified 44 (21.0%), common complication pulmonary manifestation (40/188, 21.9%), followed cerebral (5/210, 2.4%), shock (4/210, 1.9%), spontaneous bleeding (3/210, 1.4%), metabolic acidosis 3.5%) acute kidney injury (2/210, 1.0%). Unusual complications, such splenic infarction (ten patients) retinal haemorrhage (two sometimes observed. There no deaths, but case involving ECMO potentially fatal.Plasmodium infection can be fatal frequently associated various adults. frequency each seems differ countries. further investigation elucidate causes mechanisms responsible for these differences.