The intake of maqui (Aristotelia chilensis) berry extract normalizes H2O2 and IL-6 concentrations in exhaled breath condensate from healthy smokers - an explorative study

• DOI: 10.1186/s12937-015-0008-1
• Publication Date: 2015-03-18T16:48:03Z
• Authors: Daniela Vergara; Daniela Ávila; Elizabeth Escobar; Catalina Carrasco...; Andrés Sánchez; Martin Gotteland
• Keywords: Clinical nutrition; Exhaled breath condensate; Open peer review; Green coffee

Respiratory diseases are associated with pulmonary oxidative stress and inflammatory processes. Though studies in animal models suggest that dietary polyphenols improve lung injury, no intervention were carried out humans. The aim of this study was to determine whether the intake an anthocyanin-rich maqui extract improved H2O2 IL-6 concentrations exhaled breath condensates (EBCs) from asymptomatic smokers.15 smokers mild cigarette smoking (3 pack-year [2.4 - 7.7]) (mean [CI95%]) recruited exploratory longitudinal study. They ingested 2 g (polyphenol content = 5.18 ± 2.00 GAE/100 g; FRAP value 27.1 2.0 mmol Fe(++)/100 g), twice daily for two weeks. EBCs collected before after treatment changes determined by fluorimetry Elisa, respectively. EBC contents also compared those single samples 8 healthy non-smokers subjects. At baseline, higher lower than non-smokers. Maqui significantly decreased (p < 0.0002) increased 0.004) smokers. administration did not differ between non-smokers.Maqui normalizes humans habits. If confirmed, these results might be considered as interesting alternative management respiratory disorders.